- Scatman Crothers (1 film)
- Scoot McNairy (2 films)
- Scott Adsit (1 film)
- Scott Caan (1 film)
- Scott Cohen (1 film)
- Scott Dymond (1 film)
- Scott Eastwood (1 film)
- Scott G. Anderson (1 film)
- Scott Haze (1 film)
- Scott Patterson (1 film)
- Scott Poythress (1 film)
- Scott Speedman (1 film)
- Scottie Thompson (1 film)
- Sean Andrews (1 film)
- Sean Astin (2 films)
- Sean Bean (3 films)
- Sean Biggerstaff (1 film)
- Sean Connery (2 films)
- Sean Gullette (1 film)
- Sean Hayes (1 film)
- Sean Maguire (1 film)
- Sean Penn (4 films)
- Sean Rogerson (1 film)
- Sean Young (2 films)
- Seann William Scott (5 films)
- Sebastián Ayala (1 film)
- Sebastian Blyckert (1 film)
- Sebastian Koch (2 films)
- Sebastian Stan (4 films)
- Sébastien Akchoté (1 film)
- Sébastien Chabane (1 film)
- Sébastien Chassagne (2 films)
- Sébastien Pouderoux (1 film)
- Sebastien Tellier (1 film)
- Secun de la Rosa (1 film)
- Sedona Legge (1 film)
- Sehar Bhojani (1 film)
- Seidi Haarla (1 film)
- Sela Ward (1 film)
- Selena Gomez (5 films)
- Selma Blair (1 film)
- Semen Serzin (1 film)
- Senan Jennings (1 film)
- Serge Hazanavicius (1 film)
- Serge Riaboukine (2 films)
- Serge Sauvion (1 film)
- Sergej Trifunović (1 film)
- Sergi López (1 film)
- Sergio Peris-Mencheta (2 films)
- Seth Green (1 film)
