- Seth MacFarlane (4 films)
- Seth Meyers (1 film)
- Seth Rogen (14 films)
- Shahadi Wright Joseph (1 film)
- Shaheizy Sam (1 film)
- Shailene Woodley (2 films)
- Shaïn Boumedine (1 film)
- Shaine Jones (1 film)
- Shakira (1 film)
- Shameik Moore (2 films)
- Shamier Anderson (1 film)
- Shamon Brown Jr. (1 film)
- Shane Carruth (1 film)
- Shane McRae (1 film)
- Shantel VanSanten (1 film)
- Shaofeng Feng (1 film)
- Shari Eubank (1 film)
- Shari Finkelstein (1 film)
- Sharlto Copley (7 films)
- Sharon Ceccatti (1 film)
- Sharon Farrell (1 film)
- Sharon Horgan (1 film)
- Sharon Stone (1 film)
- Shaun Benson (1 film)
- Shaun Evans (1 film)
- Shaun Thomas (1 film)
- Shauna Macdonald (1 film)
- Shawn Ashmore (2 films)
- Shawn Dou (1 film)
- Shawnee Smith (2 films)
- Shelley Duvall (1 film)
- Shelley Winters (2 films)
- Sheri Moon Zombie (2 films)
- Shia LaBeouf (9 films)
- Shila Ommi (1 film)
- Shiloh Fernandez (1 film)
- Shin Ha-kyun (1 film)
- Shinpachi Tsuji (1 film)
- Shirine Boutella (1 film)
- Shirley Henderson (1 film)
- Shirley MacLaine (2 films)
- Show Luo (1 film)
- Shun Oguri (1 film)
- Shuya Sophia Cai (1 film)
- Sidse Babett Knudsen (3 films)
- Sienna Miller (1 film)
- Sifan Shao (1 film)
- Sigourney Weaver (11 films)
- Silvia Abascal (1 film)
- Silvio Orlando (1 film)
