- Shane McRae (1 film)
- Shane Carruth (1 film)
- Shamon Brown Jr. (1 film)
- Shamier Anderson (1 film)
- Shameik Moore (2 films)
- Shakira (1 film)
- Shaine Jones (1 film)
- Shaïn Boumedine (1 film)
- Shailene Woodley (2 films)
- Shaheizy Sam (1 film)
- Shahadi Wright Joseph (1 film)
- Seth Rogen (14 films)
- Seth Meyers (1 film)
- Seth MacFarlane (4 films)
- Seth Green (1 film)
- Sergio Peris-Mencheta (2 films)
- Sergi López (1 film)
- Sergej Trifunović (1 film)
- Serge Sauvion (1 film)
- Serge Riaboukine (2 films)
- Serge Hazanavicius (1 film)
- Senan Jennings (1 film)
- Semen Serzin (1 film)
- Selma Blair (1 film)
- Selena Gomez (5 films)
- Sela Ward (1 film)
- Seidi Haarla (1 film)
- Sehar Bhojani (1 film)
- Sedona Legge (1 film)
- Secun de la Rosa (1 film)
- Sebastien Tellier (1 film)
- Sébastien Pouderoux (1 film)
- Sébastien Chassagne (2 films)
- Sébastien Chabane (1 film)
- Sébastien Akchoté (1 film)
- Sebastian Stan (4 films)
- Sebastian Koch (2 films)
- Sebastian Blyckert (1 film)
- Sebastián Ayala (1 film)
- Seann William Scott (5 films)
- Sean Young (2 films)
- Sean Rogerson (1 film)
- Sean Penn (4 films)
- Sean Maguire (1 film)
- Sean Hayes (1 film)
- Sean Gullette (1 film)
- Sean Connery (2 films)
- Sean Biggerstaff (1 film)
- Sean Bean (3 films)
- Sean Astin (2 films)
