- Sean Penn (2 films)
- Sean Price Williams (1 film)
- Sean S. Cunningham (1 film)
- Sebastián Silva (2 films)
- Sébastien Betbeder (2 films)
- Sébastien Laudenbach (1 film)
- Sergio Castellitto (1 film)
- Sergio Leone (1 film)
- Sergio Pablos (1 film)
- Seth Gordon (2 films)
- Seth Grossman (1 film)
- Seth MacFarlane (3 films)
- Seth Rogen (1 film)
- Shane Acker (1 film)
- Shane Black (3 films)
- Shawn Levy (9 films)
- Shinichiro Ueda (1 film)
- Shinji Aramaki (2 films)
- Shinsuke Sato (2 films)
- Sidney Lumet (1 film)
- Simon Barrett (1 film)
- Simon J. Smith (1 film)
- Simon Kinberg (2 films)
- Simon West (3 films)
- Simon Wincer (1 film)
- Sofia Coppola (1 film)
- Sonia Kronlund (1 film)
- Sophie Fillières (1 film)
- Spike Jonze (2 films)
- Srđan Spasojević (1 film)
- Stanley Kubrick (4 films)
- Stéphan Castang (1 film)
- Stéphane Aubier (1 film)
- Stéphane Berla (1 film)
- Stéphane Cazes (1 film)
- Stéphane Foenkinos (1 film)
- Stéphane Rybojad (1 film)
- Stephen Chbosky (1 film)
- Stephen Chiodo (1 film)
- Stephen Chow (2 films)
- Stephen Daldry (2 films)
- Stephen Donnelly (1 film)
- Stephen Gaghan (1 film)
- Stephen Herek (1 film)
- Stephen Sommers (2 films)
- Stephen St. Leger (1 film)
- Steve Carr (1 film)
- Steve Hickner (1 film)
- Steve Martino (2 films)
- Steve McQueen (1 film)
