- S.J. Clarkson (1 film)
- Sacha Gervasi (1 film)
- Sam Esmail (1 film)
- Sam Fell (1 film)
- Sam Hargrave (1 film)
- Sam Mendes (5 films)
- Sam Peckinpah (2 films)
- Sam Raimi (8 films)
- Sam Taylor-Johnson (1 film)
- Sam Weisman (1 film)
- Samuel Armstrong (1 film)
- Samuel Bayer (1 film)
- Sandrine Kiberlain (1 film)
- Sarah Adina Smith (1 film)
- Sarah Smith (1 film)
- Satoshi Kon (2 films)
- Scott Derrickson (4 films)
- Scott Mann (1 film)
- Scott Moore (2 films)
- Scott Schirmer (1 film)
- Scott Stewart (1 film)
- Scott Waugh (2 films)
- Sean Anders (1 film)
- Sean Ellis (1 film)
- Sean Penn (2 films)
- Sean Price Williams (1 film)
- Sean S. Cunningham (1 film)
- Sebastián Silva (2 films)
- Sébastien Betbeder (2 films)
- Sébastien Laudenbach (1 film)
- Sergio Castellitto (1 film)
- Sergio Leone (1 film)
- Sergio Pablos (1 film)
- Seth Gordon (2 films)
- Seth Grossman (1 film)
- Seth MacFarlane (3 films)
- Seth Rogen (1 film)
- Shane Acker (1 film)
- Shane Black (3 films)
- Shawn Levy (9 films)
- Shinichiro Ueda (1 film)
- Shinji Aramaki (2 films)
- Shinsuke Sato (2 films)
- Sidney Lumet (1 film)
- Simon Barrett (1 film)
- Simon J. Smith (1 film)
- Simon Kinberg (2 films)
- Simon West (3 films)
- Simon Wincer (1 film)
- Sofia Coppola (1 film)
